News / 24 September 1998
 
  1998/OB/13

OXFORD BIOMEDICA

Announces Two New Research Collaborations

Oxford BioMedica, a world leader in the development and application of gene-based therapeutics using advanced gene delivery, announced today that it has signed exclusive research collaboration agreements with the US National Institutes of Health (NIH) and The University of North Carolina at Chapel Hill (NC, USA).

The NIH collaboration is a Cooperative Research and Development Agreement (CRADA) with the Clinical Gene Therapy Branch of the National Human Genome Research Institute and builds on Oxford BioMedica's proprietary lentiviral vector technology and the NIH's dual virus vector systems. The systems under development are expected to be applicable to a wide variety of diseases.

The North Carolina collaboration will build on the Company's lentiviral technology based on the equine infectious anaemia virus (EIAV) through a sponsored research programme in the laboratory of Dr John Olsen who has extensive experience of this area. Oxford BioMedica is the only gene therapy company that is developing vectors based on EIAV.

Oxford BioMedica's Chief Executive, Professor Alan Kingsman, said "We are delighted to be working alongside two such prestigious groups in the USA. These collaborations will further strengthen our technology platform and ensure we maintain a leading competitive position in the rapid development of effective gene-based therapeutics."

"Oxford BioMedica is particularly pleased to be increasing its research and development programmes in North America, and to be working with research groups which additionally offer the opportunity to explore clinical trials with leading centres in the USA," he added.



Notes

1. Oxford BioMedica: established in 1995, specialises in the development and application of gene-based therapeutics using advanced gene delivery technologies for the treatment of disease in the areas of: oncology, viral infection, neurobiology and genetic deficiency. Oxford BioMedica plc was floated on the UK Alternative Investment Market of the London Stock Exchange in December 1996. The Company raised £6 million (before expenses) in a recent placing and rights issue. These funds will provide the necessary funds for the continued development of the Group's candidate products.

2. Oxford BioMedica's LentiVectorT and PEGASUST systems can be used to deliver genes effectively to non-dividing cells including inter alia cells in the brain without causing inflammation. These technologies have a wide range of applications including the treatment of neurodegenerative diseases such as Parkinson's disease. The LentiVectorT can also carry anti-HIV genes to the cells of the immune system for the treatment of AIDS.

3. The National Institutes of Health (NIH) is one of the world's foremost biomedical research centres and the Federal focal point for biomedical research in the USA. The NIH conducts research in its own laboratories and supports research of non-federal scientists in universities, medical schools, hospitals and research institutions in the US and worldwide. One of the eight health agencies of the US Public Health Service, the NIH has a budget of more than $13.6 billion.

4. Further information on the NIH can be obtained from its website:
http://www.nih.gov/welcome/nihnew.html

5. Further information on The University of North Carolina at Chapel Hill can be obtained from its websites:
http://www.unc.edu and http://research.unc.edu/otd/


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For further information contact:

 

Oxford BioMedica plc
Professor Alan Kingsman, Chief Executive

Tel: +44 (0) 1865 783 000

City/Financial Enquiries
Mike Wort Mexal Communications

Tel: +44 (0) 171 432 0394

Scientific/Trade Enquiries
Emma Johnson HCC•De Facto Group

Tel: +44 (0)171 496 3300

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