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News / 13 August 1998
 
  1998/OB/12

OXFORD BIOMEDICA

Announces Interim Results For The Six Months To 30 June 1998

13 August 1998. Oxford BioMedica plc, the UK's leading gene therapy company, announces its interim results for the financial period ended 30 June 1998.

Highlights:

  • Collaborative deal completed
  • Successful £6 million fund raising
  • First clinical trial on target
  • Appointment of new chairman and non-executive director
  • Technological advances with Lentivectors™ and Hypoxia Response Element
The net loss of £1.8 million in the first half of 1998 was in line with budget. Research and development expenditure in the period was £1.3 million. At 30 June 1998 the Company had cash reserves of £5.1 million.

Financing for the immediate future was secured by a £6 million placing and rights issue in March/April 1998. This was achieved despite a very difficult financial market for the biotechnology sector, and allows the Company to forge ahead with its innovative research and development programmes and to proceed towards the first clinical trials.

Alan Goodman, Chairman of Oxford BioMedica commented: "This has been an impressive first half for the Company, building on the substantial achievements of 1997 and confirming Oxford BioMedica's position as the UK's premier gene therapy company."

The rapid pace of development of the Company's programmes continued in 1998. Regulatory documentation for the first clinical trial has been submitted. The trial, of MetXia™ for late stage breast cancer, is planned to start around the end of 1998 and run through 1999. A second trial programme for BetOvaC® (ovarian cancer) is planned for mid 1999.

There have also been impressive developments in the supporting toolbox of platform technologies. In particular the development of Lentivectors™, a new class of gene delivery vectors in which Oxford BioMedica has a unique position, has accelerated the Company's product development and is attracting world-wide interest from potential partners.

In addition, the Company has made improvements to the Hypoxia Response Element which was acquired in 1997, and the Company anticipates significant demand from future collaborative partners to use HRE in solid tumours and also in other applications.

At the beginning of the year Oxford BioMedica reported its first commercial interaction with Rhône-Poulenc Rorer. With significant progress being made in several other commercial negotiations, the Company looks forward to extending its collaborative programmes in the coming months.

Alan Kingsman, Chief Executive commented "It has always been Oxford BioMedica's intention to commercialise its technology platforms via the placing of individual technology components in other companies' product development programmes as well as through the development of its own innovative product programmes. The value of this approach is being confirmed in many of our commercial discussions."


Consolidated Profit & Loss Account
 

6 months ended
30 June 1998
(unaudited)
£

9 months ended
30 June 1997
(unaudited)
£

15 months ended
31 Dec 1997
(audited)
£

Turnover

5,002

800

2,800

Research and development

(1,321,844)

(747,675)

(1,972,309)

Administrative expenses

(665,168)

(649,888)

(1,180,416)

Operating expenses

(1,987,012)

(1,397,563)

(3,152,725)

Other operating income: grants receivable

34,846

-

-

Operating loss

(1,947,164)

(1,396,763)

(3,149,925)

 

Interest receivable

116,179

144,236

224,591

Interest payable

(53)

(432)

(432)

Loss on ordinary activities before taxation

(1,831,038)

(1,252,959)

(2,925,766)

 

Tax on loss on ordinary activities

-

-

-

Loss for the period

(1,831,038)

(1,252,959)

(2,925,766)

 

Loss per ordinary share (pence)

(2.0)

(2.1)

(4.9)


Consolidated Balance Sheet

 

As at
30 June 1998
(unaudited)
£

As at
30 June 1997
(unaudited)
£

As at
31 Dec 1997
(audited)
£

Fixed assets

     

Intangible assets

406,085

576,079

430,696

Tangible assets

957,778

886,925

1,034,402

 

1,363,863

1,463,004

1,465,098

Current assets

     

Debtors: amounts falling due within one year

266,853

243,977

224,982

Cash at bank and in hand

5,079,284

3,073,385

1,512,128

 

5,346,137

3,317,362

1,737,110

Creditors: amounts falling due within one year

383,657

346,574

441,223

Net current assets

4,962,480

2,970,788

1,295,887

Net assets

6,326,343

4,433,792

2,760,985

Capital and reserves

   

Called-up share capital

1,170,286

570,286

570,286

Share premium account

9,287,125

4,490,729

4,490,729

Other reserves

710,952

710,952

710,952

Profit and loss account (deficit)

(4,842,020)

(1,338,175)

(3,010,982)

Equity shareholders' funds

6,326,343

4,433,792

2,760,985


Consolidated Cash Flow Statement

 

6 months ended
30 June 1998
(unaudited)
£

9 months ended
30 June 1997
(unaudited)
£

15 months ended
31 Dec 1997
(audited)
£

Operating activities

     

Net cash outflow from continuing operating activities
(reconciliation to operating loss below)

(1,772,772)

(1,315,460)

(2,876,638)

Returns on investments and servicing of finance

     

Interest received

92,169

143,616

226,696

Interest paid

(53)

(432)

(432)

 

92,116

143,184

226,264

Capital expenditure and financial investment

     

Purchase of intangible fixed assets

-

(129,399)

-

Purchase of tangible fixed assets

(148,584)

(878,897)

(1,091,455)

 

(148,584)

(1,008,296)

(1,091,455)

Cash outflow before management of liquid resources and financing

(1,829,240)

(2,180,572)

(3,741,829)

Management of liquid resources

   

Transfer to deposit accounts

(5,200,000)

(4,100,000)

(4,100,000)

Transfer to current accounts

500,000

1,900,000

4,650,000

 

(4,700,000)

(2,200,000)

550,000

Financing

   

Issue of shares

6,000,000

5,253,340

5,253,340

Expenses of share issue

(603,604)

(707,031)

(707,031)

 

5,396,396

4,546,309

4,546,309

(Decrease)/Increase in cash in the period

(1,132,844)

165,737

1,354,480


Reconciliation of Operating Loss to Net Cash Outflow from Operating Activities

 

6 months ended
30 June 1998
(unaudited)
£

9 months ended
30 June 1997
(unaudited)
£

15 months ended
31 Dec 1997
(audited)
£

Continuing activities

   

Operating loss

(1,947,164)

(1,396,763)

(3,149,925)

Amortisation on intangible fixed assets

24,611

45,544

61,528

Depreciation on tangible fixed assets

128,062

55,269

163,453

Increase in other debtors

(4,973)

(85,128)

(111,194)

Increase in prepayments and accrued income

(12,888)

(117,651)

(75,315)

(Decrease)/increase in trade creditors

(4,564)

35,647

77,938

Increase in other taxation and social security

7,379

23,162

26,411

Increase in accruals and deferred income

36,765

124,460

130,466

Net cash outflow from continuing operating activities

(1,772,772)

(1,315,460)

(2,876,638)



Notes

1. Copies of this statement are being sent to all shareholders. Copies are also available at the registered office of the Company, Medawar Centre, Oxford Science Park, Oxford OX4 4GA

2. On 25 March 1998 the Company issued 45,742,862 new ordinary shares of 1p at 10p per share, raising cash proceeds of £4,574,286 before expenses. On 17 April 1998 a further 14,257,138 new ordinary shares of 1p each were issued in a 1 for 4 rights issue at 10p per share. The proceeds of the rights issue before expenses was £1,425,714.

3. The interim results are unaudited and do not constitute statutory accounts within the meaning of section 240 of the Companies Act 1985. The interim results are prepared in accordance with the accounting policies set out in the Report and Accounts for the 15 months ended 31 December 1997. The financial information relating to the 15 months ended 31 December 1997 has been extracted from the full report and accounts for that period which have been filed with the Registrar of Companies. The report of the auditors on those accounts was unqualified.

The loss per ordinary share has been calculated on a weighted average number of 90,490,266 shares in issue during the period (9 months ended 30 June 1997: 59,504,722, 15 months ended 31 December 1997: 60,256,794). In calculating the weighted average number of shares, the number of shares in issue prior to the rights issue has been adjusted to reflect the bonus element of the rights issue.


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For further information contact:

 

Oxford BioMedica plc
Professor Alan Kingsman, Chief Executive

0171 488 4040 (13 August)
01865 783000 (thereafter)

City/Financial Enquiries
Mike Wort Mexal Communications

Tel: +44 (0) 171 432 0394

Scientific/Trade Enquiries
Emma Johnson HCC•De Facto Group

Tel: +44 (0)171 496 3300

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