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News 15 July 2008
 

 

2008/OB/23

OXFORD BIOMEDICA REPORTS FURTHER DATA FROM INTERIM REVIEW OF TROVAX® PHASE III TRIST STUDY

Oxford, UK - 15 July 2008: Oxford BioMedica (LSE: OXB), announced that it has written to all investigators participating in the TRIST study summarising the background to the independent Data Safety Monitoring Board's recent recommendations. The letter also summarises the study procedures to continue the follow up of all patients enrolled into the study.

This letter has been made publically available on the Company's web site here.

Oxford BioMedica is grateful to all investigators participating in TRIST for their continued support of this important ongoing study.

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Notes

1. Oxford BioMedica plc

Oxford BioMedica (LSE: OXB) is a biopharmaceutical company specialising in cancer immunotherapy and gene-based therapies. The Company was established in 1995, as a spin-out from Oxford University, and is listed on the London Stock Exchange.

The Company has a platform of gene delivery technologies, which are based on highly engineered viral systems. Oxford BioMedica also has in-house clinical, regulatory and manufacturing know-how. TroVax® is the Company's therapeutic vaccine, which is in clinical development for multiple solid cancers. The product is licensed to sanofi-aventis for global development and commercialisation. Oxford BioMedica has three other products in clinical development, including ProSavin®, a novel gene-based treatment for Parkinson's disease, in a Phase I/II trial. The Company is underpinned by over 80 patent families, which represent one of the broadest patent estates in the field. The Company has a staff of approximately 85. Oxford BioMedica has collaborations with sanofi-aventis, Wyeth, Sigma-Aldrich, MolMed and Virxsys. Technology licensees include Biogen Idec, Merck & Co, GlaxoSmithKline and Pfizer.

Further information is available at www.oxfordbiomedica.co.uk

2. TroVax®

TroVax is Oxford BioMedica's novel therapeutic cancer vaccine, which is being developed in collaboration with sanofi-aventis. It is designed specifically to stimulate an anti-cancer immune response and has potential application in most solid tumour types. TroVax targets the tumour antigen 5T4, which is broadly distributed throughout a wide range of solid tumours. The presence of 5T4 is correlated with poor prognosis. The product consists of a Modified Vaccinia Ankara vector, which delivers the gene for 5T4 and stimulates a patient's body to produce an anti-5T4 immune response. This immune response destroys tumour cells carrying the 5T4 antigen.

 

For further information please contact:

 

Oxford BioMedica plc
Mike McDonald, Chief Executive Officer
Nick Woolf, Chief Business Officer

Tel: +44 (0)1865 783 000

JPMorgan Cazenove Limited
James Mitford/Gina Gibson

Tel: +44 (0)20 7588 2828

City/Financial Enquiries
Lisa Baderoon/Mark Court/Mary-Jane Johnson
Buchanan Communications

Tel: +44 (0)20 7466 5000

Scientific/Trade Press Enquiries
Holly Griffiths/Katja Stout/Claire Mosley
College Hill
Tel: +44 (0)20 7457 2020
US Enquiries
Thomas Fechtner
The Trout Group LLC
Tel: +1 646 378 2900

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