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Clinical trials

Oxford BioMedica is currently recruiting for clinical trials as detailed below. For further information, please visit the www.clinicaltrials.gov website or contact your doctor or primary healthcare professional.

If you are currently participating in one of our clinical trials and you have a medical emergency, please contact either your study centre or the Oxford BioMedica switchboard on +44 (0) 1865 783 000.

SAR 422459

Stargardt disease

A Phase I/IIa dose escalation safety study of SAR 422459, administered to patients with Stargardt macular degeneration.

ClinicalTrials.gov identifier: NCT01367444
Principal Investigator: Professor David Wilson
Casey Eye Institute
Oregon Health & Science University
Portland, Oregon, 97239-3098, USA
Principal Investigator: Professor Jose-Alain Sahel
Centre Hospitalier Nationale d'Ophthalmologie des Quinze-Vingts
Paris, France, 75571

SAR 421869

Retinitis pigmentosa associated with Usher syndrome type 1B

A Phase I/IIa dose escalation safety study of SAR 421869, administered to patients with retinitis pigmentosa associated with Usher syndrome type 1B.

ClinicalTrials.gov identifier: NCT01505062
Principal Investigator (US): Professor Richard Weleber
Oregon Health and Science University
Casey Eye Institute
Portland, Oregon 97239-4197, USA

Trials being conducted by our partners:



A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma (SKOPOS)
ClinicalTrials.gov ID: NCT01569919
Principal Investigator: Jason F Lester, FRCR, MRCP
Velindre Cancer Centre
Cardiff, South Wales, United Kingdom, CF14 2TL


Colorectal cancer

A pilot study to assess the effect of regulatory T-cell depletion on 5T4-containing MVA(TroVax®)vaccination in patients with inoperable metastatic colorectal cancer (TaCTiCC)
EudraCT Number: 2010-024380-41
Principal Investigator: Dr Andrew Godkin
Henry Wellcome Building
School of Medicine
Heath Park
Cardiff, CF14 4XN, United Kingdom



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